Professor Jason Shoemaker focuses on modeling the immune response to viral lung infections, particularly influenza. His research integrates experimental studies with computational modeling to understand immune dynamics and the molecular mechanisms underlying severe infections. Shoemaker’s lab aims to identify biomarkers for excessive inflammatory responses, which can lead to more severe disease outcomes. Insights gained from his work could enhance treatment strategies for viral infections.
"Predicting infectious etiology and severity in hospitalized pediatric pneumonia using blood cytokine biomarkers"
Duray AM, Lee B, Abood RN, Musa S, Kainaroi S, Michaels MG, Shoemaker JE, Alcorn JF. Front Pediatr. 2025, 13, 1693879
"A detailed kinetic model of Eastern equine encephalitis virus replication in a susceptible host cell"
Larkin CI, Dunn MD, Shoemaker JE, Klimstra WB, Faeder JR. A detailed kinetic model of Eastern equine encephalitis virus replication in a susceptible host cell. PLoS Comput Biol. 2025, 21, 6, e1013082
"Sex-based differences in persistent lung inflammation following influenza infection of juvenile outbred mice"
Huckestein BR, Antos D, Manni ML, Zeng K, Miller LM, Parenteau KL, Gelhaus SL, Mullett SJ, Shoemaker JE, Alcorn JF. Am J Physiol Lung Cell Mol Physiol. 2024, 327, 2, L189-L202
"Mathematical Modeling Suggests That Monocyte Activity May Drive Sex Disparities during Influenza Infection"
Liparulo TS, Shoemaker JE. Viruses. 2024, 16, 6, 837
"Attenuation of A(H7N9) influenza virus infection in mice exposed to cigarette smoke."
Fukuyama S, Shoemaker JE, Zhao D, Nagajima N, Tomita Y, Maemura T, da Silva Lopes TJ, Watanabe T, Yamayoshi S, Hasegawa H, Kawaoka Y. Npj Viruses. 2024, 2, 1,16